Why do we get Fat – and how does it make us ill?
Obesity is a major and growing threat to global public health. In this talk Stephen O’Rahilly will focus on two broad questions. Firstly, in the face of modern “obesogenic” environment to which most of us are exposed, why do some people become obese while others remain lean. Is this purely down to conscious choices and are lean people in some way “morally superior”? Or is there some strong biological predisposition influencing a person’s risk of becoming obese? The evidence for such strong biological predisposition, what processes it influences, and what that will mean for changes in societal attitudes, treatment and prevention will be presented.
The extent to which obesity has adverse impact on health also varies enormously between individuals. Why, for example, do some severely obese people avoid developing diabetes, even into a late age, while other, only moderately overweight people, develop Type 2 diabetes quite young Professor O’Rahilly will describe how growing understanding of the biology of fat cells is providing new insights into how our bodies can deal with excess calories in a healthy or unhealthy way
About the Speaker
Stephen O’Rahilly graduated in Medicine from University College Dublin in 1981. From 1982 to 1991 he undertook postgraduate clinical and research training in general medicine, diabetes and endocrinology in London, Oxford and Harvard. In 1991 he obtained a Wellcome Trust Senior Clinical Fellowship and established his laboratory at the University of Cambridge. In 1996 he was appointed to a newly created Chair of Metabolic Medicine and in 2002 to the Chair of Clinical Biochemistry and Medicine at the University of Cambridge. He is the Co-Director of the Wellcome Trust-MRC Institute of Metabolic Science and Director of the MRC Metabolic Diseases Unit. His research 52 has been concerned with the elucidation of the basic causes of obesity and Type 2 diabetes at a molecular level and the translation of those discoveries into improved diagnosis and therapy for patients. His work has uncovered several previously unrecognised genetic causes of these diseases including some that are amenable to specific treatment. He has won many awards for his work, including the Society for Endocrinology Medal and the Clinical Investigator Award of the Endocrine Society, and he gave the Harveian Oration of the Royal College of Physicians, London, in 2016. He is a also a member of several international academies and societies. In 2013 he was appointed a Knight Bachelor for services to medical research. He has a continuing commitment to clinical practice and the teaching of medical students, successfully mentoring young scientists and clinician-scientists.
Menu for Supper
Chicken with Diane sauce with new potatoes and vegetables
Goat's cheese and red onion quiche (v)
Fresh fruit salad
N.B. the Lit & Phil office have to inform venues of catering numbers approximately 7 days before an event so please make sure you book as early as possible to avoid disappointment.