Osteoarthritis: how new ‘precision medicine’ will cause a revolution in the management of an old disease
This talk will discuss the history, cause and clinical presentation of osteoarthritis. Despite being the most common non-infective disease in the world, we really know remarkably little about it. This is best reflected by the fact we have very few and not particularly effective treatments other than joint replacement in end stage disease. Medicine is about to undergo a revolution that will change the way we make diagnoses, investigate disease and treat it. The talk will examine how this revolution in medicine may at last lead to better understanding and completely new treatments for this disabling disease that affects a third of all adults over the age of 45. We will discuss the way in which the “omics revolution” will change how we diagnose osteoarthritis, how we use that information to stratify (i.e. recognise distinct subclasses of) osteoarthritis and finally how that will lead to new treatments that can be targeted at osteoarthritis in individual patients (precision medicine).
This talk will interest young people if they are looking for a career as a healthcare professional or a biologist, if you think you might be one of the third of the population that is likely to develop osteoarthritis, or if you have an enquiring mind.
About the Speaker
Tony Freemont has been Clinical Professor of Bone and Joint Pathology at The University of Manchester for 25 years. His research group studies the biology and management of “degenerative” joint disease and has developed novel treatments for back pain based on reversing degeneration of the intervertebral discs. In addition, he leads a Medical Research Council funded group that takes novel molecular biomarkers and turns them into tests in the NHS. So far the group has taken six new tests into hospital use with the potential to save the NHS £100m a year and with more tests in the pipeline. He is also director of the University’s KNH Centre for Biomedical Egyptology which is using biomarker-based technology to better understand disease from the late bronze age to modern times.
Menu for Supper
For School Bookings: Pizza and refreshments before the lecture (6pm)
For Members of the Society:
Beef Goulash & boiled potatoes or Baked Salmon fillet with lemon butter & braised leeks or Mature Cheddar & Red Onion Pie (v)
with a choice of the following sides: roast potatoes, steamed market vegetables, pilaf rice
Raspberry Bavarois or Treacle Tart
N.B. the Lit & Phil office have to inform venues of catering numbers approximately 7 days before an event so please make sure you book as early as possible to avoid disappointment.